Amniotic Injections

What Conditions Can DPMx Treat?  DPMx is often used to treat musculoskeletal conditions, such as:

• Tendinopathy (with or without partial tendon tears)
• Plantar fasciitis
• Osteoarthritis
• Other tendon, bone or ligament injuries

It may also be used for other conditions as determined by your healthcare provider. Note that some uses, particularly for orthopedic conditions, may be considered investigational.

How is the Procedure Performed?

1. Preparation: Your healthcare provider will evaluate your condition using a physical exam, medical history, and possibly imaging (e.g., ultrasound or MRI) to confirm that DPMx is appropriate for you.
2. Injection: The DPMx allograft is injected directly into the affected area (e.g., tendon, joint, or soft tissue) using a syringe. The procedure is typically performed in an outpatient setting and may be guided by ultrasound for precision. 
3. Duration: The injection itself usually takes a few minutes, though the entire visit may last 30–60 minutes, including preparation and post-procedure instructions.
4. Pain Management: A local anesthetic may be used prior to the procedure to minimize discomfort during the injection.

What to Expect After the Procedure

• Immediate Effects: You may experience mild soreness or swelling at the injection site for a few days. This is normal and should subside.
• Recovery: Most patients can resume normal activities within a day or two, but your provider may recommend avoiding strenuous activities for a short period (e.g., 1–2 weeks).This may vary pending your individual condition and provider recommendations.
• Results: Pain relief and improved function may be noticeable within a few weeks, with optimal results often seen after 6-8 weeks. Some patients may require more than one injection, depending on the condition and response to treatment.

 Follow-Up: Your provider will schedule follow-up visits to monitor your progress, possibly using imaging or pain scales to assess improvement.

Potential Benefits

• Pain Reduction: Studies have shown that amniotic and umbilical cord allografts may reduce pain in conditions like Achilles tendinopathy and plantar fasciitis.
• Tissue Repair: The allograft contains proteins and growth factors that may support tissue healing and reduce inflammation.
• Minimally Invasive: The injection is a non-surgical option, potentially avoiding the need for more invasive procedures.
• Low Risk of Rejection: Amniotic and umbilical cord tissues are non-immunogenic, meaning they are unlikely to cause an immune reaction.

Potential Risks and Side Effects  While DPMx injections are generally considered safe, there are some risks, including:

• Injection Site Reactions: Temporary pain, swelling, or redness at the injection site.
• Disease transmission Risk: Although donor tissue is rigorously screened for infectious diseases, there is a minimal risk of disease transmission, as no screening process can guarantee absolute safety.
• Infection: Rare, but possible, as with any injection procedure
• Allergic Reaction: Extremely rare, as the product is thoroughly processed and rigorously tested, but some patients may be sensitive to umbilical cord tissue.
• Lack of Efficacy: The treatment may not work for everyone, and some conditions may require additional therapies.
• Investigational Status: For some uses, such as osteoarthritis, the treatment is considered experimental by insurers like Medicare, as more research is needed to confirm long-term benefits.

Is DPMx Amniotic Injection Therapy Covered By My Insurance? This type of therapy is considered experimental by Medicare and Commercial Insurers. At this time they state that there is insufficient evidence-based literature to support coverage for the treatment of musculoskeletal conditions.Research continues to be ongoing in the field of amniotic tissue and other orthobiologic products.

 FDA Regulation: DPMx follows strict guidelines from the Food and Drug Administration (FDA) as a registered HST/P under 21 CFR Part 1271, accredited by the American Association of Tissue Banks (AATB) and Current Goods and Manufacturing Practice (cGMP) certified.